Nasolabial Fold Treatment with Growth Factor Injections – Woman in Her 20s (Case 1)

Written and Medically Reviewed by:
Specialized Clinic for Nasolabial Fold and Wrinkle Treatments
Osaka Houreisen Skin Clinic / Tokyo Houreisen Skin Clinic / Nagoya Houreisen Skin Clinic
Dr. Shinya Sasagawa, Aesthetic Dermatologist
Representative of Shingetsukai Medical Corporation View Doctor’s Profile →

This case features a woman in her 20s who was concerned about the appearance of her nasolabial folds (smile lines). Although significant age-related deepening of nasolabial folds is less common at her age, she had dry skin and was bothered by fine lines that remained around her mouth after smiling. She also noticed that foundation tended to settle into her nasolabial folds when wearing makeup.

She underwent growth factor injections to improve the appearance of her nasolabial folds. Here, we present her results before treatment and four months after the procedure.

Before Treatment / 4 Months After Growth Factor Injections

Patient’s Concerns Before Treatment

Although she was still in her 20s, the patient felt self-conscious about her visible nasolabial folds and the way foundation accumulated in the creases.

She also had dry skin and was concerned that the lines around her mouth remained visible even after she stopped smiling. Nasolabial folds can sometimes remain noticeable even after smiling , including in younger individuals.

Before Growth Factor Treatment

For more information about why makeup tends to settle into nasolabial folds and what treatment options may help address this concern, please see our article on the causes and treatment of foundation settling into nasolabial folds .

Growth Factor Treatment Performed

In this case, growth factor injections were administered to the nasolabial fold area.

Growth factor injections are a treatment designed to improve the appearance of nasolabial folds by promoting the production of collagen and elastin in the skin. Rather than evaluating the results immediately after injection, we monitor the changes over the following months.

Results 4 Months After Treatment

4 Months After Growth Factor Treatment

These photographs were taken four months after treatment. Even when wearing makeup, foundation was less likely to settle into the nasolabial folds, addressing one of the patient’s main concerns.

→ View More Growth Factor Treatment Cases for Nasolabial Folds